5th Principal Investigators Meeting Agenda

5th Principal Investigators Meeting
Innovative Molecular Analysis Technologies Program
June 28 -30, 2004
Catamaran Resort Hotel
San Diego, California

Agenda

MONDAY, JUNE 28, 2004
7:30 a.m. - 8:45 a.m.		Registration and Breakfast
8:45 a.m. - 9:00 a.m		Welcome Ed Monachino, NCI
9:00 a.m. - 9:30 a.m.		NCI Technology Initiatives Greg Downing, D.O., Ph.D., NCI
Session 1—Generating the Knowledge Base for Cancer Research
9:30 a.m. - 10:00 a.m.		End of Sequence Profiling (ESP): The Structural Analysis of Tumor Genomes Colin Colins, Ph.D., University of California - San Francisco
10:00 a.m. - 10:30 a.m		Protein Knockout, A Novel Reverse Genetic Tool for Dissecting the Function of Oncoproteins During Normal Development and in Antagonizing Tumorgenicity Pengbo Zhou, Ph.D., Weill Medical College of Cornell University
10:30 a.m. - 11:00 a.m.		BREAK
11:00 a.m. - 11:30 a.m.		Identification of Frequent Chromosomal Aberrations in Hepatocellular Carcinoma from Gene Expression Microarray Data Kyle Furge, Ph.D., Van Andel Research Institute
11:30 a.m. - 12:00 p.m		Functional-Based Identification of New Target Genes for Cancer Brian Davis, Ph.D., Ordway Research Institute
12:00 p.m. - 1:00 p.m.		LUNCH
Managing Intellectual Property in Academia and through Commercial Ventures
1:00 p.m. - 1:30 p.m.		From Idea to Clinic: Aligning the Stakeholders to Generate Clinical Tests from Research Ideas Kathy Danenberg, Ph.D, Response Genetics, Inc., and UCLA
1:30 p.m. - 2:00 p.m.		Institutional Concerns about Technology Transfer and Intellectual Property Kathy Ku, M.S.C.E., Stanford University
2:00 p.m. - 2:30 p.m.		NIH-Sponsored Research and Technology Transfer Karen Maurey, M.S., NCI-TTO
2:30 p.m. - 3:00 p.m.		Bridging the Funding Gap Paul Radspinner, M.B.A., Wisconsin Alumni Research Foundation
3:00 p.m. - 3:30 p.m.		BREAK
3:30 p.m. - 4:00 p.m.		New Concepts on FDA Guidance for Genetic and Genomic Technologies Elizabeth Mansfield, Ph.D., FDA
4:30 p.m. - 5:00 p.m.		NCI IP Policy Change Greg Downing, D.O., Ph.D., NCI
5:00 p.m. - 6:00 p.m		Panel Discussion: Dannenberg, Ku, Maurey, Radspinner, Mansfield, Downing
6:00 p.m. - 9:00 p.m.		Poster Session
TUESDAY, JUNE 29, 2004
7:30 a.m. - 8:30 a.m.		Registration & Breakfast
8:30 a.m. - 9:30 a.m.		Keynote: Modeling Tumors as Complex Biosystems Tom Deisboeck, Ph.D., Harvard University
Session 2—Creating Tools for Discovery
9:30 a.m. - 10:00 a.m.		Development of a Self Assembling Protein Array Niroshan Ramachandran, Ph.D., Harvard Medical School
10:00 a.m. - 10:30 a.m.		Optomechanical Chips for Molecular Profiling of Cancer Arun Majumdar, Ph.D., University of California - Berkeley
10:30 a.m. - 11:00 a.m.		BREAK
11:00 a.m. - 11:30 a.m.		PAP: A Platform Technology Steve Sommer, M.D., Ph.D., City of Hope National Medical Center/Beckman Research Institute
11:30 a.m. - 12:00 p.m.		Rapid and Sensitive Genetic Mutation Detection by Tandem SSCP/Heteroduplex Analysis in a Microchip Electrophoresis System Annelise Barron, Ph.D., Northwestern University
12:00 p.m. - 1:00 p.m.		LUNCH
Session 3 - Moving New Tools into the Lab & Clinic
1:00 p.m. - 1:30 p.m.		Recovery of DNA, RNA, and Protein from Archival Formalin-Fixed, Paraffin-Embedded Tissue Sections Based on the Antigen Retrieval Principle Clive Taylor, M.D., Ph.D., University of Southern California
1:30 p.m. - 2:00 p.m.		Use of Oligonucleotide-Based Microarray to Interrogate Promoter Hypermethylation Tim Huang, Ph.D., The Ohio State University Comprehensive Cancer Center
2:00 p.m. - 2:30 p.m.		Profiling Ras-Activated Signal Transduction Pathways Nancy Allbritton, M.D., Ph.D., University of California - Irvine
2:30 p.m. - 3:00 p.m.		Gel Protein Extraction Platform for Ultrasensitive Gel Protein Identification Cheng Lee, Ph.D., Calibrant Biosystems
3:00 p.m. - 3:30 p.m.		BREAK
3:30 p.m. - 4:00 p.m.		IMAT RFAs Greg Downing, D.O., Ph.D., NCI
4:00 p.m. - 4:15 p.m.		SBIR Update Jennifer Couch, Ph.D., NCI
4:15 p.m. - 5:00 p.m.		Beyond IMAT: Other NIH and NCI Funding Opportunities Jennifer Couch, Ph.D.; NCI, Tracy Lugo, Ph.D., NCI
5:00 p.m. - 9:00 p.m.		Poster Session
WEDNESDAY, JUNE 30, 2004
7:30 a.m. - 8:30 a.m .		Registration & Breakfast
8:30 a.m. - 9:30 a.m.		Keynote: Challenges and Opportunities in Translational Cancer Research Cheryl Willman, M.D., University of New Mexico
Session 4 - Human Cancer Care
9:30 a.m. - 10:00 a.m.		Gene-specific DNA Methylation for Cancer Diagnosis: A Study of 53 Promoters in 10 Breast Cancer Patients Victor Levenson, M.D., Ph.D. Robert H. Lurie Comprehensive Cancer Center
10:00 a.m. - 10:30 a.m.		Proteomics of Hepatic Neoplasia in a Synchronous Rat Model Ruth Hogue Angeletti, Ph.D., Albert Einstein College of Medicine
10:30 a.m. - 11:00 a.m.		BREAK
11:00 a.m. - 11:30 a.m.		Bcr-Abl Kinase Assays for Gleevec Resistance in Chronic Myeloid Leukemia Steve Kron, M.D., Ph.D., University of Chicago
11:30 a.m. - 12:00 p.m.		Panel Discussion: Speakers from Session 1 and 2
12:00 p.m.		ADJOURN