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3rd Principal Investigators Meeting Agenda

3rd Principal Investigators Meeting
Innovative Molecular Analysis Technologies Programs
July 8-10, 2002
Westfields International Conference Center
Chantilly, Virginia


MONDAY, JULY 8, 2002
7:00 a.m. - 8:00 a.m. Registration
Breakfast and Poster Setup
8:00 a.m. Keynote: Challenges in Cancer Research
Dr. Ed Harlow, Harvard Medical School
Session 1-Generating the Knowledge Base for Cancer Research
9:00 a.m. Fundamental Clustering Approach To Genomic Analysis
Dr. Ray Cho, Ingenuity Systems, Inc.
9:30 a.m. Highly Parallel Single Cell Monitoring of Receptor-Triggered Membrane Translocation of a Calcium Sensing Protein Module
Dr. Mary Teruel, Stanford University
10:00 a.m. Break
10:30 a.m. Vertical Arrays for Gene Expression Analysis
Dr. John Welsh, Sidney Kimmel Cancer Center
11:00 a.m. The C. elegans ORFeome: Version 1.0 and Beyond
Dr. David Hill, Dana-Farber Cancer Institute
11:30 a.m. Application of the Directional Change Assessment Algorithm on Microarray Data To Underscore Markers that Distinguish Ovarian, Breast and Prostate Cancer
Dr. Peter Tolias, Center for Applied Genomics, Public Health Research Institute
noon Lunch
1:00 p.m. Presentation: High Throughput Genome Technologies: Clinical and Industrial Applications
Dr. Mike Hogan, University of Arizona
Session 2-Creating Tools for Discovery
2:00 p.m. Protein Profiling Arrays
Dr. Mark Chee, Illumina, Inc
2:30 p.m. STowards Protein-Detecting Microarrays: Novel Methods for the Isolation of Synthetic, High Affinity Protein Ligands
Dr. Tom Kodadek, University of Texas Southwestern Medical Center
3:00 p.m. Break
3:30 p.m. Blind Sources Separation for Partial Volume Correction in Microarray Data Analysis
Dr. Yue Wang, The Catholic University of America
4:00 p.m. Global Scanning of Single Nucleotide Variations
Dr. Sherman Weissman, Yale University
4:30 p.m. ROMA, a Method for All Seasons
Dr. Robert Lucito, Cold Springs Harbor Laboratory
5:00-9:00 p.m. Poster Session and Reception

7:00-8:00 a.m. Registration
Breakfast and Poster Setup
Keynote Panel: Moving from Discovery To Application
8:00 a.m. FDA- Capt R.K. Leedham
8:30 a.m. PTO- Dr. John Doll
9:00 a.m. Dawnbreaker- Dr. Jenny Servo
9:30 a.m. Questions and Answers
10:00 a.m. Break
Session 3-Collaboration: The Key To Success
10:30 a.m. NCI Staff Overview
10:45 a.m. Dr. Tim Huang, Ellis Fischel Cancer Center, University of Missouri-Columbia
11:15 a.m. Dr. Richard Levenson, Cambridge Research and Instrumentation
11:45 a.m. Questions and Answers
Noon Lunch
1:00 p.m. Presentation: Success Story
Dr. Bill Kaelin, Dana-Farber Cancer Institute
Session 4-Moving New Tools into the Lab & Clinic
2:00 p.m. Development of a Reliable, Routine Process To Isolate/Enrich Cancer Cells from Bone and Peripheral Blood Samples
Dr. Jeff Chalmers, Ohio State University
2:30 p.m. Automated Measurement of Ras and Rho Activation in Cancer
Dr. Gerry Boss, University of California, San Diego
3:00 p.m. Break
3:30 p.m. Novel Proteome Methods for Global Quantitative Protein Profile Comparisons of Human Breast Cancer Metastasis
Dr. David Speicher, The Wistar Institute
4:00 p.m. Harnessing the SCF Ubiquitination Machinery for Targeted Proteolysis
Dr. Pengbo Zhou, Weill Medical College of Cornell University
4:30 p.m. High Throughput Proteomics and Genome Annotation Using CD-Tagging
Dr. Jonathan Jarvik, Carnegie Mellon University
5:00 p.m. - 9:00 p.m. POSTER SESSION AND RECEPTION

7:00 a.m. - 8:00 a.m. Breakfast
8:00 a.m. Presentation: Success Stories-Moving Discoveries into Application
Dr. Tim Triche, University of Southern California
Session 5-Exploring Human Cancer
9:00 a.m. Automated Minimal Residual Disease Quantification
Dr. Deirdre Meldrum, University of Washington
9:30 a.m. Mutation Analysis for Tuberous Sclerosis: Technology Development and Molecular Epidemiology Studies
Dr. Sandra Dabora, Brigham and Women's Hospital
10:00 a.m. Break
10:30 a.m. Novel Imaging Methods for Gene Discovery in Cancer
Dr. John Condeelis, Albert Einstein College of Medicine
11:00 a.m. Molecular Staging of Human Squamous Cell Skin Cancer
Dr. Jim Gale, University of New Mexico
11:30 a.m. Presentation: Success Stories-Moving Discoveries into Application
Dr. Kathy Klinger, Genzyme Corpoartion
12:30 p.m. Closing Remarks