THURSDAY, JULY 6, 2000

5:00-6:30 p.m.

Registration

6:30 p.m.

Welcome
Dr. Carol Dahl, National Cancer Institute

6:45 p.m.

Plenary Lecture: Future Directions in Cancer Research
Dr. Richard Klausner, Director, National Cancer Institute

7:30 p.m.

Session 1: Highlights in DNA Analysis
Session Chair: Dr. Deirdre Meldrum, University of Washington

7:40 p.m.

Multiparameter Analysis of Human Epithelial Tumors by Laser Scanning Cytometry
Dr. Stanley Shackney, Allegheny-Singer Research Institute

8:05 p.m.

Optomechanical Detection of Biomolecular Recognition and Interactions
Dr. Arun Majumdar, University of California, Berkeley

8:30 p.m.

High-Throughput Methylation Analysis using CpG Island Microarray
Dr. Tim Hui-Ming Huang, University of Missouri

8:55 p.m.

Highly Selective Isolation of Unknown Mutations in Diverse DNA Fragments: New Potential for Multiplex Screening in Cancer
Dr. G. Mike Makrigiorgos, Dana-Farber Cancer Institute

9:20 p.m.

High-Resolution Sequencing of Mixed Population of DNA Molecules
Dr. Nadia Lifshitz, Biophotonics Corporation

9:45 p.m.

Detection of Genomic Alteration by Molecular Combing
Dr. Aaron Bensimon - Pasteur Institute

10:10 p.m.

Adjourn

FRIDAY, JULY 7, 2000

Registration

7:00 a.m.

Breakfast

Poster set up

Plenary Lecture: The Cancer Genome Anatomy Project
Dr. Robert Strausberg, National Cancer Institute

8:30 a.m

Session 2: Emerging Technologies for RNA Analysis
Session Chair: Dr. Mark Chee, Illumina, Inc.

8:40 a.m.

Messenger RNA Profiling by Single Molecule Counting
Dr. Paul Lizardi, Yale University

9:10 a.m.

Randomly Self-Assembled Bead-Based Arrays for Highly Parallel Analysis of Nucleic Acids
Dr. Mark Chee, Illumina, Inc.

9:40 a.m.

Fish & Chips
Dr. Robert Singer, Albert Einstein College of Medicine

10:10 a.m.

Break

10:45 a.m.

Session 3: Advances in Protein Expression Analysis
Session Chair: Dr. Richard Smith, Pacific Northwest National Laboratory

10:50 a.m.

Proteomics Applied to the Search for Cancer Markers in Human Body Fluids
Dr. N. Leigh Anderson, Large Scale Proteomics Corporation

11:15 a.m.

Quantitative Proteome Analysis: Methods and Applications
Dr. Reudi Aebersold, University of Washington

11:40 a.m.

Microfabricated Fluidic Devices for Protein and Peptide Mapping
Dr. J. Michael Ramsey, Oak Ridge National Laboratory

12:05 p.m.

Lunch

1:30 p.m

Session 3: Advances in Protein Expression Analysis
Session Chair: Dr. Richard Smith, Pacific Northwest National Laboratory

1:40 p.m.

The C. elegans ORFeome Cloning Project
Dr. Marc Vidal, Dana-Farber Cancer Institute

2:05 p.m.

Sigma Receptors as a Biomarker of the Proliferative Status of Solid Tumors
Dr. Robert Mach, Wake Forest University

2:30 p.m.

Plenary Lecture: The Director's Challenge
Dr. Barbara Conley, National Cancer Institute

3:00 p.m.

Break

3:30 p.m.

Session 4: New Strategies for Protein Structure and Function Analysis
Dr. Daniel Jay, Tufts University

3:40 p.m.

Structural Genomics Target Selection for Cancer-Related Proteins Across Complete Genomes
Dr. Terry Gaasterland, The Rockefeller University

4:10 p.m.

The Electronic Detection of Interactions Between Ligands and Cell Surface Receptors
Dr. Cynthia Bamdad, Minerva Biotechnologies Corporation

4:40 p.m.

Identification of Novel Breast Cancer Agents Using Functional Genomics
Dr. Marek Liyanage, Aurora Biosciences

5:10 p.m.

A High Throughput Screen for Cancer Cell Invasiveness Using Chromophore-Assisted Laser Inactivation
Dr. Daniel Jay, Tufts University

5:30-10:00 p.m.

Poster Session and Reception

7:00 p.m.

Special Session
NCI Resources: Tools to Speed Cancer Research

8:00 p.m.

Special Session
Phased Innovation Awards: Review and Transitions

SATURDAY, JULY 8, 2000

7:00 a.m.

Breakfast

8:00 a.m.

Plenary Lecture:
Molecular Epidemiology and the Genetic Annotation Initiative
Dr. Kenneth Buetow, National Cancer Institute

8:30 a.m.

Highlights in DNA Analysis
Dr. Deirdre Meldrum, University of Washington

8:50 a.m.

Emerging Technologies for RNA Analysis
Dr. Mark Chee, Illumina, Inc.

9:10 a.m.

Advances in Protein and Functional Analysis
Dr. Richard Smith, Pacific Northwest National Laboratory

9:30 a.m.

New Strategies for Protein Structure and Function Analysis
Dr. Daniel Jay, Tufts University

9:50 a.m.

Discussion

10:15 a.m.

Closing Remarks

Lunch